The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 1994
Filed:
Sep. 05, 1991
Silva Rodriquez, Ciudad de la Habana, CU;
Selman H Sosa, Ciudad de la Habana, CU;
Guillen Nieto, Ciudad de la Habana, CU;
Saturnino H Martinez, Ciudad de la Habana, CU;
Julio R Maso, Ciudad de la Habana, CU;
Lidia I Perez, Ciudad de la Habana, CU;
Juan M Grillo, Ciudad de la Habana, CU;
Vivian M Cordova, Ciudad de la Habana, CU;
Sonia G Blanco, Ciudad de la Habana, CU;
Beatriz T Santos, Ciudad de la Habana, CU;
Jesus A del Valle Rosales, Ciudad de la Habana, CU;
Evelin C Menendez, Ciudad de la Habana, CU;
Anabel A Acosta, Ciudad de la Habana, CU;
Edelgis C Rodriquez, Ciudad de la Habana, CU;
Silian C Leon, Ciudad de la Habana, CU;
Alexis M Lasa, Ciudad de la Habana, CU;
Abstract
The present invention is concerned with a method for the isolation of a nucleotide sequence which codes for a protein having a molecular weight of about 64,000 daltons, which is located on the outer membrane of N. meningitidis, as well as with the recombinant DNA obtained therefrom, which is used for the transformation of a host microorganism. The technical object pursued with the invention is the identification of a nucleotide sequence coding for a highly conserved and common protein for the majority of pathogenic Neisseria strains, the production of this protein with a high level of purity and in commercially useful amounts using the recombinant way, so that it can be used in diagnostic methods and vaccine preparations with a broad immunoprotection spectrum.