The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 25, 1994

Filed:

May. 31, 1991
Applicant:
Inventors:

Carol A Toth, Sharon, MA (US);

Peter Thomas, Pembroke, MA (US);

Sibusisiwe M Maswoswe, Ashland, MA (US);

Joseph V Briggman, Westford, MA (US);

Assignees:

Applied Biotechnology, Inc., Cambridge, MA (US);

New England Deacons Hospital Corp., Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ; G01N / ;
U.S. Cl.
CPC ...
530350 ; 424-9 ; 436 64 ; 436503 ; 436543 ; 436813 ; 5303877 ; 53038825 ; 5303893 ; 530828 ;
Abstract

Disclosed is a protein that specifically binds carcinoembryonic actigen (CEA) in the presence of divalent cation in vitro. This protein has a molecular weight of about 20 kD as determined by SDS-polyacrylamide gel electrophoresis, is glycosylated, and includes the amino acid sequence set forth in the Sequence Listing as SEQ ID NO:4. Also disclosed are antibodies that recognize the CEA binding protein, methods of detecting carcinoma, methods of treating carcinoma, and a kit for screening a patient for carcinoma.


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