The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 1994

Filed:

May. 17, 1991
Applicant:
Inventors:

Ronald H Erickson, Baltimore, MD (US);

Kenneth J Natalie, Jr, Baltimore, MD (US);

Michael J Pontecorvo, Belcamp, MD (US);

Waclaw J Rzeszotarski, Millersville, MD (US);

Assignee:

Scios Nova, Inc., , DE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ; A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514320 ; 514212 ; 5142282 ; 5142335 ; 514255 ; 514318 ; 514324 ; 514337 ; 514422 ; 514432 ; 514456 ; 540596 ; 544 62 ; 544151 ; 544145 ; 544376 ; 546193 ; 546196 ; 546202 ; 546269 ; 546274 ; 548525 ; 549 23 ; 549400 ; 549401 ;
Abstract

Sigma binding site agents having the formula ##STR1## which are useful to inhibit sigma binding site-induced activity, pharmaceutical compositions including these agents, and methods of using these agents to inhibit sigma binding site-induced activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented agents.


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