The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 1994

Filed:

Jun. 05, 1991
Applicant:
Inventors:

Nobuo Ikekawa, Musashino, JP;

Yoshiro Kobayashi, Tokyo, JP;

Yoko Tanaka, Delmar, NY (US);

Tadashi Eguchi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07J / ;
U.S. Cl.
CPC ...
514167 ; 552653 ;
Abstract

Fluorine-containing vitamin D.sub.3 analogues of the formula [I]: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are independently hydrogen atom, a chemically inactive hydroxy-protecting group, an acyl having 2 to 8 carbon atoms or an alkyl having 1 to 8 carbon atoms, and n is an integer of 4 to 6, which have excellent pharmacological activities, particularly anti-tumor activity owing to differentiation-inducing activity and are useful for the prophylaxis and treatment of various tumors and intermediates therefore.


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