The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 11, 1994

Filed:

Apr. 03, 1992
Applicant:
Inventor:

Wilfred P Shum, West Chester, PA (US);

Assignee:

Arco Chemical Technology, L.P., Wilmington, DE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ;
U.S. Cl.
CPC ...
435280 ;
Abstract

A process for enriching or improving the optical purity of an asymmetric epoxidation reaction mixture is provided wherein the chiral epoxy alcohol enantiomer present in minor amounts is effectively separated from the predominant chiral epoxy alcohol enantiomer. The minor enantiomer is converted to an epoxy ester by stereoselective transesterification using a carboxylic acid derivative such as an enol ester and a lipase enzyme. The desired major chiral epoxy alcohol enantiomer is then recovered or reacted in situ to form a chiral epoxy alcohol derivative.


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