The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 28, 1993

Filed:

Oct. 25, 1989
Applicant:
Inventor:

John W Clitherow, Sawbridgeworth, GB;

Assignee:

Glaxo Group Limited, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07F / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514340 ; 514399 ; 514400 ; 514439 ; 546-5 ; 546-6 ; 546210 ; 548106 ; 548205 ; 5483355 ;
Abstract

The invention relates to salts formed between basic H.sub.2 -receptor antagonists and a complex of bismuth with a carboxylic acid, and solvates of such salts, excluding salts in which the basic H.sub.2 -receptor antagonist is ranitidine. Examples of suitable carboxylic acids are citric acid and tartaric acid. Examples of basic H.sub.2 -receptor antagonists are cimetidine, sufotidine famotidine and nizatidine. The salts are useful in the treatment of gastrointestinal disorders, particularly gastroduodenal conditions. The salts show the antisecretory activity associated with the basic H.sub.2 -receptor antagonist together with antibacterial activity against Campylobacter pylori, and they also possess cytoprotective properties.


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