The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 21, 1993
Filed:
Nov. 10, 1992
Applicant:
Inventors:
Tatsuo Toyoda, Kawanishi, JP;
Toshihiro Fujioka, Kitakatsuragi, JP;
Kunio Hayashi, Kadoma, JP;
Masuhisa Nakamura, Takarazuka, JP;
Naofumi Hashimoto, Daito, JP;
Assignee:
Shionogi & Co., Ltd., Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544137 ; 544238 ; 544335 ; 544406 ; 546146 ; 546168 ; 546209 ; 546275 ; 548200 ; 548214 ; 548215 ; 548253 ; 548255 ; 5482668 ;
Abstract
A following dipeptide derivative of the following formula (I) is provided, which is capable of inhibiting the enzymatic activity of renin and thereby depressing the renin-angiotensin system and lowering the blood pressure. ##STR1## wherein: R.sup.1 is C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.3 -C.sub.10 cycloalkyl, aryl, or heterocyclic radical;