The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 14, 1993
Filed:
Jul. 31, 1991
Applicant:
Inventors:
David R Brittain, Rochdale, GB;
Steven P Brown, Bude, GB;
Anthony L Cooper, Bude, GB;
Jethro L Longridge, Macclesfield, GB;
Jeffrey J Morris, Sandbach, GB;
John Preston, Knutsford, GB;
Linda Salter, Macclesfield, GB;
Assignee:
Imperial Chemical Industries PLC, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ;
U.S. Cl.
CPC ...
514617 ; 514456 ; 514520 ; 514619 ; 514622 ; 514866 ; 549398 ; 549404 ; 549407 ; 558404 ; 558413 ; 564166 ; 564167 ; 564172 ; 564174 ; 564175 ; 564181 ; 564183 ;
Abstract
The invention concerns novel N-phenylacetyl and related acyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives.