The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 1993
Filed:
Jun. 07, 1991
Applicant:
Inventors:
Ronald G Almquist, Palo Alto, CA (US);
Atsuro Nakazato, Saitama, JP;
Assignee:
SRI International, Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
514 19 ; 514 18 ; 530330 ; 530331 ;
Abstract
Novel compounds useful as renin inhibitors are provided. The compounds are hydroxyazido derivatives having the structural formula ##STR1## wherein the substituents R.sub.1 through R.sub.7 are as defined herein. Analogs of these compounds which are ketozaido derivatives are also provided. Additionally disclosed re methods for using the novel compounds to treat hypertension, and pharmaceutical compositions containing the compounds. Of particular interest are formulations for oral administration.