The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 1993

Filed:

Dec. 13, 1990
Applicant:
Inventors:

Hans O Ribi, San Mateo, CA (US);

Todd A Guion, Burlingame, CA (US);

Joseph R Murdoch, Burlingame, CA (US);

John C Scott, Los Gatos, CA (US);

Victor Pan, Burlingame, CA (US);

Glenda L Choate, Belmont, CA (US);

Assignee:

Biocircuits Corporation, Sunnyvale, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
436501 ; 436164 ; 436172 ; 436527 ; 436528 ; 436531 ; 436805 ; 422681 ; 422 8205 ; 422 8208 ; 422 8209 ; 435291 ;
Abstract

Apparatus and methods are provided for the detection of analytes. A polyunsaturated polymerized lipid layer is employed, which is anisotropic, has a member of a specific binding pair bound to an end of the lipids, and whose optical characteristics are modified upon complex formation between the specific binding pair member and its complementary member. By providing for polarized light, linear and/or circular, one can detect the presence of complex formation by the change in the optical characteristics of the film. Polarizers, analyzers, and wave plates are employed for providing for a light signal which can be analyzed and related to the presence of an analyte in a sample.


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