The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 07, 1993

Filed:

Oct. 26, 1990
Applicant:
Inventors:

Toshitsugu Matsuki, Matsuyama, JP;

Noritsugu Saiki, Matsuyama, JP;

Shingo Emi, Daito, JP;

Assignee:

Teijin Limited, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; G01N / ; C08G / ; C07K / ;
U.S. Cl.
CPC ...
435181 ; 435180 ; 435803 ; 435815 ; 436531 ; 436532 ; 528399 ; 530413 ; 530815 ; 530816 ;
Abstract

A phosphazene polymer for immobilizing biologically active substances such as enzymes is prepared that does not lower activity originally possessed by the biologically active substance and does not contain a functionality which can adsorb undesired substances. The polymer has organic radicals having a functional group capable of binding a biologically active substance and organic radicals which are non-reactive and hydrophilic. The non-reactive and hydrophilic organic radicals are preferably prepared by reacting a side chain of the polymer having a primary amino group with formaldehyde or by diazotizing the primary amino group followed by hydrolysis to form a hydroxyl group. A biologically active substance immobilized on the polymer can be used to separate a substance that has affinity for the immobilized biologically active substance.


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