The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 1993
Filed:
Apr. 22, 1992
Applicant:
Inventors:
Vladimir Beylin, Ann Arbor, MI (US);
Huai G Chen, Ann Arbor, MI (US);
Om P Goel, Ann Arbor, MI (US);
Mark E Marlatt, Grass Lake, MI (US);
John G Topliss, Ann Arbor, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07C / ;
U.S. Cl.
CPC ...
546136 ; 546134 ; 549 26 ; 549 27 ; 549388 ; 549392 ; 560 27 ; 560 28 ; 560 38 ; 562401 ; 562441 ; 562443 ; 562444 ; 562452 ; 562456 ; 562455 ; 548200 ; 548215 ; 548230 ;
Abstract
Novel cyclic amino acids which are useful in preparing biologically active peptides as well as a process for the preparation of D and L enantiomers of the cyclic amino acids are described where an N-protected derivative of the racemic cyclic amino acid is treated with (-)cinchonidine and the resulting salt resolved into the desired enantiomers, as well as derivatives thereof and valuable intermediates used in the process.