The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 1993

Filed:

Sep. 09, 1992
Applicant:
Inventors:

Patrick L Coleman, Minneapolis, MN (US);

Thomas A Kotnour, Faribault, MN (US);

Richard J Rolando, Oakdale, MN (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08F / ; C08F / ; C08F / ; C08F / ; C08F / ; C08F / ; C08F / ; C08L / ; C08L / ; A61K / ; G01N / ;
U.S. Cl.
CPC ...
525204 ; 525 70 ; 525 80 ; 525 87 ; 525 52 ; 525 53 ; 525206 ; 525222 ; 525227 ; 525232 ; 525240 ; 525241 ; 525263 ; 525279 ; 525284 ; 525302 ; 525308 ; 525315 ; 525319 ; 525320 ; 525322 ; 525324 ; 525353 ; 5253591 ; 5253593 ; 525375 ; 525379 ; 525384 ; 525385 ; 525386 ; 525 73 ; 427-2 ; 436531 ; 514-2 ; 428461 ; 428462 ;
Abstract

Graft copolymers and processes for the preparation thereof are provided. The copolymers comprise a base polymer having grafted thereto a monomeric 2-alkenyl azlactone. The surface properties of the graft copolymers can be modified by binding thereto nucleophilic reagents comprising further functional groups with desired properties. Further, the amount of azlactone available at the surface of a graft copolymer for binding to such nucleophilic reagents can be controlled by selecting a surface against which the graft copolymer is formed. The graft copolymers exhibit desirable thermoplastic, melt flow, and adhesion properties and are particularly useful for immobilizing proteins. Methods of immunoassay based on the immobilization of proteins are also disclosed. Another utility of the graft copolymers involves the compatibilizing of immiscible polymer blends.


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