The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 1993
Filed:
Mar. 13, 1992
Applicant:
Inventors:
Huw M Davies, Clemmons, NC (US);
Elie Saikali, Winston-Salem, NC (US);
Steven R Childers, Winston-Salem, NC (US);
Assignee:
Wake Forest University, Winston-Salem, NC (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
514304 ; 546124 ;
Abstract
Preparation of biologically active tropane derivatives of novel configurations. The compounds are prepared by decomposing vinyldiazomethanes in the presence of pyrroles to provide a bicyclic ring containing the basic tropane ring system which is then reacted with an aryl Grignard reagent in the presence of a copper (I) or (II) salt to provide 3-aryltropane derivatives.