The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 1993
Filed:
Oct. 10, 1991
Applicant:
Inventors:
Assignee:
Merck Sharp & Dohme Limited, Hoddesdon, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514214 ; 514210 ; 514216 ; 514252 ; 514253 ; 514254 ; 514256 ; 514269 ; 514272 ; 514274 ; 540582 ; 540598 ; 540601 ; 544238 ; 544298 ; 544300 ; 544310 ; 544315 ; 544316 ; 544317 ; 544318 ; 544319 ; 544320 ; 544322 ; 544324 ; 544328 ; 544331 ; 544333 ; 544405 ;
Abstract
The present invention provides pyrazines, pyridazines or pyrimidines, or salts or prodrugs thereof, substituted on one of the ring carbon atoms thereof with a non-aromatic azacyclic or azabicyclic ring system; and independently substituted on each of the other ring carbon atoms with a substituent of low lipophilicity or a hydrocarbon substituent; which compounds stimulate central muscarinic acetylcholine receptors and therefore are useful in the treatment of neurological and mental illnesses.