The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 09, 1993

Filed:

Jun. 14, 1991
Applicant:
Inventors:

Wayne L Cody, Saline, MI (US);

Annette M Doherty, Ann Arbor, MI (US);

John X He, Ann Arbor, MI (US);

Assignee:

Warner-Lambert Company, Morris Plains, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
514 14 ; 514 13 ; 514 15 ; 514 16 ; 514 17 ; 514 18 ; 530326 ; 530327 ; 530328 ; 530329 ; 530330 ; 530331 ; 530317 ;
Abstract

Novel linear and monocyclic antagonists of endothelin are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling hypertension, myocardial infarction, metabolic, endocrinological, and neurological disorders, congestive heart failure, endotoxic shock, subarachnoid hemorrhage, arrhythmias, asthma, acute renal failure, preeclampsia, and diabetes.


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