The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 1993
Filed:
Apr. 27, 1992
Alexander H Chu, Buffalo Grove, IL (US);
Abbott Laboratories, Abbott Park, IL (US);
Abstract
A process for the manufacture of vancomycin.HCl which does not require preparation of a phosphate intermediate. The process consists of loading a vancomycin onto a suitable adsorbent and eluting the vancomycin solution therefrom with an ammonium solvent followed by loading the vancomycin solution onto a suitable adsorbent and eluting the purified, vancomycin solution therefrom with a solvent of alcohol and acid. The purified vancomycin is then crystallized from the solution by combining the solution with a sufficient amount of NH.sub.4 Cl to provide a pH of about 2.0 to about 3.5. The crystals are then dissolved in solution. The dissolved solution is combined with acid and the vancomycin recrystallizes from the solution.