The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 1993
Filed:
Jun. 25, 1992
Satoru Nagamura, Shizuoka, JP;
Hiromitsu Saito, Mishima, JP;
Eiji Kobayashi, Numazu, JP;
Katsushige Gomi, Susono, JP;
Kyowa Hakko Kogyo Co., Ltd., Tokyo, JP;
Abstract
DC-89 derivatives represented by the formula: ##STR1## wherein X represents hydrogen or CO.sub.2 CH.sub.3 ; and ##STR2## wherein Z represents Cl or Br; R represents hydrogen, CONR.sup.1 R.sup.2 (in which R.sup.1 and R.sup.2 independently represent hydrogen, a straight-chain or branched alkyl group having 1 to 4 carbon atoms or phenyl) or ##STR3## (in which n represents an integer of 0 to 4; R.sup.3 represents CH.sub.2, ##STR4## oxygen, N--CH.sub.3, or N--CH.sub.2 CONR.sup.1 R.sup.2 in which R.sup.1 and R.sup.2 have the same significances as defined above); and W represents hydrogen or ##STR5## (in which W.sup.1 and W.sup.2 independently represent hydrogen or OR.sup.2 in which R.sup.4 represents a straight-chain or branched alkyl group having 1 to 4 carbon atoms or a straight-chain or branched alkenyl group having 2 to 4 carbon atoms, and pharmaceutically acceptable salts thereof have an excellent anti-tumor and antibacterial activity and are expected to be useful as anti-tumor compositions and antibacterial compositions.