The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 1993
Filed:
Jul. 25, 1986
Applicant:
Inventors:
Robert Wydro, Framingham, MA (US);
Edward Cohen, Natick, MA (US);
William Dackowski, Hopkinton, MA (US);
Johan Stenflo, Malmo, SE;
Ake Lundwall, Lund, SE;
Bjorn Dahlback, Malmo, SE;
Assignee:
Genzyme Corporation, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ; C12N / ; C12N / ; C12N / ; C07K / ; C07H / ;
U.S. Cl.
CPC ...
435 696 ; 435 691 ; 4351723 ; 4353201 ; 4352351 ; 4352402 ; 536 235 ; 530350 ; 935 19 ; 935 32 ; 935 41 ; 935 57 ; 935 62 ; 935 70 ;
Abstract
Disclosed are a transformed mammalian cell that produces biologically active Protein S, and a vector for effecting the transformation of the cell. produces biologically active human Protein S, and the vector used to effect the transgenesis of the cell. The vector disclosed includes DNA encoding mature human Protein S, under the transcriptional control of a eukaryotic metallothionein gene, and also includes the transforming region of the bovine papilloma virus genome, and a fragment of SV40 DNA.