The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 1993

Filed:

Sep. 28, 1992
Applicant:
Inventor:

Alan S Horn, AW Groningen, NL;

Assignee:

Whitby Research, Inc., Richmond, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514248 ; 514249 ; 514259 ; 514261 ; 514299 ; 514300 ; 514306 ; 514311 ; 514359 ; 514364 ; 514367 ; 514375 ; 514406 ; 514415 ; 514443 ; 514456 ; 514469 ; 544235 ; 544237 ; 544277 ; 544283 ; 544353 ; 546112 ; 546117 ; 546122 ; 546138 ; 546174 ; 546176 ; 548126 ; 548152 ; 548179 ; 548180 ; 548217 ; 548257 ; 548260 ; 548261 ; 5483625 ; 548504 ; 549 43 ; 549 49 ; 549 58 ; 549407 ; 549467 ;
Abstract

Certain novel compounds having the structural formula ##STR1## where R.sub.2, R.sub.3 and R.sub.4 are each selected from the group consisting of H and OA; A is H or is selected from the group consisting of hydrocarbyl radicals, e.g. lower alkyl radicals, i.e. methyl, ethyl, propyl, etc., or ##STR2## wherein R.sub.5 is selected from the group consisting of hydrocarbyl radicals, e.g. alkyl and aromatic residues; n is 2 or 3; and R.sub.1 is selected from the group consisting of organic radicals having fused aromatic rings, that is, radicals comprising at least two rings that share a pair of carbon atoms or share a carbon and nitrogen atom are useful for inducing a dopaminergic response and reducing the intraocular pressure in a mammal.


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