The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 1993

Filed:

Jul. 17, 1992
Applicant:
Inventors:

Akinobu Matsuyama, Niigata, JP;

Teruyuki Nikaido, Niigata, JP;

Yoshinori Kobayashi, Niigata, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ; C12R / ; C12R / ;
U.S. Cl.
CPC ...
435146 ; 435141 ; 435280 ; 435822 ; 435824 ; 435830 ; 435836 ; 435852 ; 435854 ; 435856 ; 435857 ; 435853 ; 435873 ; 435874 ; 435885 ; 435911 ; 435921 ; 435930 ;
Abstract

2-Oxo-4-phenylbutyric acid is treated with a microorganism, which has been optionally treated, capable of asymmetrically reducing 2-oxo-4-phenylbutyric acid into either (R)-2-hydroxy-4-phenylbutyric acid or (S)-2-hydroxy-4-phenylbutyric acid, and the (R)-2-hydroxy-4-phenylbutyric acid or (S)-2-hydroxy-4-phenylbutyric acid thus produced is recovered to thereby give optically active 2-hydroxy-4-phenylbutyric acid. The optically active 2-hydroxy-4-phenylbutyric acid is an important intermediate in the synthesis of various drugs such as a remedy for hypertension.


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