The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 1993

Filed:

Dec. 13, 1991
Applicant:
Inventors:

Juan P Ranieri, Madrid, ES;

Antonio F Gomez-Pamo, Madrid, ES;

Luis C Llamas, Madrid, ES;

Jesus A Armendariz, Tres Cantos, ES;

Juan A Leal Ojeda, Madrid, ES;

Carmen G Benito, Segovia, ES;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C08B / ; C07H / ; C07H / ;
U.S. Cl.
CPC ...
536124 ; 536 185 ; 536 51 ; 536 53 ; 536 54 ; 536 55 ; 536 551 ; 536126 ;
Abstract

The present invention consists in a process for obtaining polymers with antiviral activity which is characterized in that beginning with oligo or polysaccharides with a specific structure, polymers with a specific number of carbonyl groups are obtained by oxidation; in that the carbonyl groups of the oxidized oligo/polysaccharides are made to react with amino groups of molecules carrying amino and sulfonated groups, such as aliphatic aminosulfonates, in water or in mixtures of water with water-miscible solvents, under specific temperature, time, and pH conditions, giving rise to polymers carrying sulfonated groups, which are purified by conventional processes; in that the sulfonated polymers thus obtained have antiviral activity and either lack or present very low toxicity and anticoagulant activity, and are thus suitable for the production of pharmaceutical preparations suitable for use in topical or systemic antiviral therapy in humans or in animals. It is applicable in the pharmaceutical industry.


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