The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 1993

Filed:

Sep. 06, 1989
Applicant:
Inventors:

Christopher J Murphy, Davis, CA (US);

Ted W Reid, Davis, CA (US);

Mark J Mannis, Carmichael, CA (US);

Bradley A Foster, Davis, CA (US);

James S Cullor, Woodland, CA (US);

Michael E Selsted, Los Angeles, CA (US);

Robert I Lehrer, Santa Monica, CA (US);

Tomas Ganz, Los Angeles, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
514 12 ; 435-1 ; 4352403 ; 514 13 ; 514 14 ; 514887 ; 514912 ; 514914 ; 530324 ; 930190 ;
Abstract

A method for treating cutaneous and corneal wounds as well as certain microbial-related diseases comprises topically applying a defensin peptide to the affected tissue. The compositions comprise a natural, synthetic, or analog defensin molecule having both a mitogenic activity capable of stimulating cell growth and an antimicrobial activity capable of inhibiting the growth of a wide variety of pathogens. In addition to therapeutic use, the defensins are useful as mitogens in cell and tissue culture media.


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