The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 1993
Filed:
Sep. 30, 1991
Applicant:
Inventors:
Assignee:
Quadra Logic Technologies Inc., Vancouver, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514410 ; 514-2 ; 514 43 ; 540145 ;
Abstract
Methods to prepare intermediates for the conjugation of active ingredients to hydrophilic carriers are described. The polyhydroxylated carriers are first derivatized to convert the hydroxyls to leaving groups and then reacted with an alkylene diamine in the presence of a reducing agent. The resulting derivatized carrier can then be coupled to substituents containing carboxyl groups in the presence of dehydrating agents.