The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 24, 1993
Filed:
Mar. 26, 1992
Hitoshi Tone, Tokushima, JP;
Seiji Sato, Tokushima, JP;
Hideaki Sato, Tokushima, JP;
Katsumi Tamura, Tokushima, JP;
Shigeharu Tamada, Tokushima, JP;
Kazumi Kondo, Naruto, JP;
Tomoyuki Kawaguchi, Tokushima, JP;
Yoshimasa Nakano, Tokushima, JP;
Yasuyuki Kita, Kashiwara, JP;
Shuji Akai, Takatsuki, JP;
Hiromichi Fujioka, Minoo, JP;
Yasumitsu Tamura, Takarazuka, JP;
Katsuhide Matoba, Kawanishi, JP;
Youichi Taniguchi, Tokushima, JP;
Shinji Nishitani, Naruto, JP;
Satoshi Hayakawa, Nishinomiya, JP;
Toshinori Kaneyasu, Naruto, JP;
Yoshihiko Ito, Kyoto, JP;
Masahiro Murakami, Kyoto, JP;
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
The novel indole derivatives and salts thereof represented by the general formula (1) ##STR1## possess, for example, an inhibitory effect against superoxide (O.sub.2.sup.-) released from the macrophage cells of guinea pig by stimulation and an anti-albuminuria activity against Masugi nephritis, and are useful in various clinical fields as an agent for preventing and treating diseases and cases associated with the above superoxide radical, for example, autoimmune diseases (e.g. rheumatism), arteriosclerosis, ischemic disease, ischemic encephalopathia, hepatic insufficiency and renal insufficiency, and also as an agent for preventing and treating nephritis.