The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 1993

Filed:

Apr. 25, 1990
Applicant:
Inventors:

Cleo Connolly, Livonia, MI (US);

Annette M Doherty, Ann Arbor, MI (US);

Harriet W Hamilton, Chelsea, MI (US);

William C Patt, Chelsea, MI (US);

Ila Sircar, Ann Arbor, MI (US);

Assignee:

Warner-Lambert Company, Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ; C07D / ;
U.S. Cl.
CPC ...
514 19 ; 514 18 ; 514359 ; 530331 ; 5483315 ; 5483147 ; 5483124 ;
Abstract

The invention concerns novel renin-inhibitory compounds which contain an amino-substituted heterocycle at the P.sub.2 position. These are useful for treating renin-associated hypertension, congestive heart failure, glaucoma, hyperaldosteronism, and diseases caused by retroviruses including HTLV-I and -III. Processes for preparing the compounds, compositions containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension, or hyperaldosteronism.


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