The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 1993
Filed:
Oct. 07, 1991
Applicant:
Inventors:
Brian L Bray, Graham, NC (US);
Maynard E Lichty, Durham, NC (US);
John J Partridge, Chapel Hill, NC (US);
John P Turnbull, Greenford, GB;
Assignee:
Glaxo Group Limited, Greenford, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07B / ; C07D / ;
U.S. Cl.
CPC ...
544276 ;
Abstract
Synthesis of the triol of formula (I) or its amine-protected derivative from a cyclopentene of the formula (II) or its amine-protected derivative: ##STR1## via steps including oxidation to the aldehyde, migration of the double bond, reduction of the aldehyde moiety back to the alcohol grouping and 1,2-cis-dihydroxylation of the double bond.