The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 1993
Filed:
Oct. 06, 1992
Applicant:
Inventors:
Sandor Hosztafi, Monostorpalyi, HU;
Sandor Makleit, Debrecen, HU;
Laszlo Szilagyi, Debrecen, HU;
Kalmany Zsupan, Tiszavasvari, HU;
Assignee:
Alkaloida Vegyeszeti Gyar Rt., Tiszavasvari, HU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514282 ; 546 45 ; 546 46 ;
Abstract
The present invention relates to novel morphinane-skeletoned compounds of the formula (I) ##STR1## wherein Y in-NH phenyl or --NH dintro phenyl, Z is --CH.sub.2 -- CH.sub.2, R.sub.2 is hydroxyl and R.sub.3 is H or methyl, the steric isomers and the pharmaceutically acceptable salts thereof, a novel process for producing the same and pharmaceutical compositions comprising the same as active ingredients. The novel compounds can be used in the therapy as analgetic or morphine-antagonistic agents.