The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 1993
Filed:
Sep. 08, 1989
Applicant:
Inventors:
Maurizio Zanetti, La Jolla, CA (US);
Petar Lenert, San Diego, CA (US);
Edward Golub, La Jolla, CA (US);
Daniel Kroon, Bridgewater, NJ (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
530324 ; 530326 ; 530350 ; 530412 ; 530413 ; 530300 ;
Abstract
Polypeptides having a segment capable of binding to immunoglobulin heavy chain variable regions (V.sub.H) in an antigen independent manner have been described. These polypeptides can be used to form complexes with V.sub.M containing molecules for diagnostic purposes and to increase the affinity of the antibody for its antigen. Additionally, the polypeptides of the invention can be used to separate V.sub.H containing molecules from solution to form isolated V.sub.H or V.sub.H depleted compositions.