The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 27, 1993
Filed:
Jul. 22, 1991
Applicant:
Inventors:
Ron Majocha, Wayland, MA (US);
Charles A Marotta, Cambridge, MA (US);
Sayeeda Zain, Pittsford, NY (US);
Assignees:
The McLean Hospital, Belmont, MA (US);
University of Rochester, Rochester, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ; C12N / ;
U.S. Cl.
CPC ...
435-71 ; 435-72 ; 435-721 ; 43524027 ; 5303881 ; 436501 ; 436506 ;
Abstract
Monoclonal antibodies to a 28-mer peptide present within A4-amyloid are described. These antibodies exhibit unexpected specificity for amyloid plaque structures previously unrecognized in Alzheimer's disease brains. These monoclonal antibodies are useful as reagents for use in assays and imaging of A4-amyloid in Alzheimer's disease patients.