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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5229509 B1

PDFFull Text
Date of Patent:
Jul. 20, 1993

Filed:

Mar. 11, 1992

Process for the preparation of 3-chloro-cefem compounds

Applicant:
Inventors:

Rosa M Nieves Elvira, Madrid, ES;

Santiago Conde Ruzafa, Madrid, ES;

Jose R Fernandez Lizarbe, Madrid, ES;

Assignee:

Antibioticos, S.A., , ES;

Attorney:

Sterne, Kessler, Goldstein & Fox

Primary Examiner:

Thurman K Page

Assistant Examiner:

Jyothsna Venkat

Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
540218 ; 540215 ;
Abstract

The process comprises a series of stages essentially comprising the protection of the functional groups of the side chain of Ampicillin, esterification of the acid group, oxidation to sulphoxide, expansion of the thiazole ring to a thiazine ring, ozonolysis of the exomethylene cefam derivative obtained, substitution of the hydroxyl group by chlorine and de-protection of the functional groups, in which the order of some stages can be varied without affecting the final result.

Find Patent Forward Citations

Nieves Elvira, Rosa. (1993). Process for the preparation of 3-chloro-cefem compounds (U.S. Patent No. 5229509). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5229509

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