The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 1993
Filed:
Aug. 01, 1990
Applicant:
Inventors:
Peter E Maligres, La Jolla, CA (US);
Kyriacos C Nicolaou, La Jolla, CA (US);
Assignee:
Scripps Clinic and Research Foundation, La Jolla, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07C / ; A61K / ; A61K / ; A61K / ; C07F / ;
U.S. Cl.
CPC ...
514 75 ; 514 82 ; 514 85 ; 514 86 ; 514 89 ; 514 90 ; 514 91 ; 514 94 ; 514 95 ; 514 96 ; 514 99 ; 514100 ; 544232 ; 544243 ; 544244 ; 544337 ; 546 22 ; 546 23 ; 546 24 ; 548112 ; 548113 ; 548119 ; 548413 ; 548414 ; 548415 ; 549-5 ; 549-6 ; 549218 ; 549220 ; 560 21 ; 560 51 ; 560 59 ; 560 60 ; 560 61 ; 560 64 ; 560 65 ; 560 66 ; 560 81 ; 568 15 ;
Abstract
Phosphine oxide-terminated allene-ene-yne compounds are disclosed that possess DNA-cleaving, antimicobial and tumor growth-inhibiting properties. Methods of making and using those compounds are also disclosed.