The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 1993
Filed:
Feb. 19, 1991
Milton L Hammond, Somerville, NJ (US);
James V Heck, Scotch Plains, NJ (US);
Robert A Zambias, Springfield, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or hydroxyl; R.sub.2 is hydrogen; hydroxyl or methyl, R.sub.3 is hydrogen or hydroxyl; R.sub.4 is C.sub.5 -C.sub.23 alkyl, C.sub.5 -C.sub.23 alkenyl, aryl or substituted aryl; R.sub.5 is --CH.sub.2 OH, --CH(CH.sub.3)OH, --CH(CH.sub.2 CONH.sub.2)OH; R.sub.6 is --CH.sub.2 OH or --CH(CH.sub.3)OH; R is --CH.sub.2 OH or --CH(CH.sub.3)OH; provided that when R.sub.4 is --(CH.sub.2).sub.8 CH(CH.sub.3)CH.sub.2 CH(CH.sub.3)C.sub.2 H.sub.5, R.sub.5 is --CH.sub.2 OH or --CH(CH.sub.3)OH. The compounds are useful as antimicrobial agents, especially as antifungal agents.