The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 1993
Filed:
Sep. 28, 1988
Applicant:
Inventors:
Irwin Fridovich, Durham, NC (US);
Douglas J Darr, Timberlake, NC (US);
Wayne F Beyer, Bahama, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07C / ;
U.S. Cl.
CPC ...
514612 ; 514616 ; 564114 ; 564152 ; 564153 ; 435189 ; 424944 ; 424D / ;
Abstract
The invention relates to a water-soluble complex formed between a chelating agent and manganese and pharmaceutical compositions thereof. The complex is a low molecular weight mimic of superoxide dismutase. The invention further relates to a method of using the complex comprising treating plant and animal cells with an amount of the complex sufficient to reduce or prevent superoxide radical-induced toxicity.