The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 1993
Filed:
Apr. 23, 1992
Siegfried Stengelin, Hofheim am Taunus, DE;
Wolfgang Ulmer, Eppstein/Taunus, DE;
Paul Habermann, Eppstein/Taunus, DE;
Eugen Uhlmann, Glashutten/Taunus, DE;
Brian Seed, Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
Hoechst Aktiengesellschaft, Frankfurt, DE;
Abstract
Fusion proteins are obtained in high yields if a mixed oligonucleotide is constructed which codes for the ballast constituent of the fusion protein. The oligonucleotide mixture is introduced in a vector in such a manner that it is functionally linked to a regulatory region and to the structural gene for the desired protein. Appropriate host cells are transformed with the plasmid population obtained in this manner and the clones producing a high yield of coded fusion protein are selected.