The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 1993
Filed:
Mar. 15, 1991
Tohru Suzuki, Tokyo, JP;
Hiroyuki Ikeda, Tokyo, JP;
Kazuyo Ikeda, Urawa, JP;
Tsugikazu Tomono, Kashiwa, JP;
Sadayoshi Sekiguchi, Sapporo, JP;
Takeji Ohtani, Tokyo, JP;
Seigi Suzuki, Aichi, JP;
Mitsubishi Rayon Co., Ltd., Tokyo, JP;
The Japanese Red Cross Society, Tokyo, JP;
Abstract
Crude immunoglobulin G isolated from human blood plasma is treated according to a conventional technique (such as the tricalcium phosphate adsorption method) to remove aggregates therefrom to such an extent that they are not detectable by gel filtration analysis. In order to produce an aqueous solution of immunoglobulin G having a reduced anticomplementary activity, the resulting solution is then filtered through a porous polyolefin membrane having a pore size larger than the molecular size of immunoglobulin G, in the presence of a stabilizer having surface activity. The aqueous solution of immunoglobulin G so produced is suitable for use in intravenous injection because its anticomplementary activity is low.