The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 1993

Filed:

Mar. 01, 1991
Applicant:
Inventors:

Sheryl L Henderson, Weare, NH (US);

Donald F Wallach, Hollis, NH (US);

Rajiv Mathur, Nashua, NH (US);

Assignee:

Micro-Pak, Inc., Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; B01J / ;
U.S. Cl.
CPC ...
4284022 ; 106312 ; 264-41 ; 264-43 ; 264-432 ; 264-433 ; 264-46 ; 264-47 ; 424450 ; 436829 ; 514832 ;
Abstract

The present invention relates to the production of lipid vesicles having a moderately volatile material such as a perfluorocarbon or a silicone oil encapsulated therein. In another aspect, lipid vesicles having a gas-filled center or core are made. The lipid vesicles having gas-filled central core are made by dehydrating vesicles having the moderately volatile liquid encapsulated in the central core. This drives off the water first, allowing the moderately volatile liquid to stabilize the vesicle structure as it dries, finally forming a central void which can refract light. The preferred vesicles of the invention are paucilamellar vesicles.


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