The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 08, 1993

Filed:

Dec. 30, 1988
Applicant:
Inventors:

Steven P Kramer, Kew Gardens, NY (US);

David M Valenzuela, Franklin Square, NY (US);

Frederick H Reynolds, Jr, Syosset, NY (US);

John M Sorvillo, Merrick, NY (US);

Assignee:

Oncogene Science, Inc., Uniondale, NY (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C07K / ; C12P / ;
U.S. Cl.
CPC ...
43524027 ; 53038824 ; 5303911 ; 5303913 ; 435 7021 ; 4351722 ;
Abstract

This invention provides a monoclonal antibody which specifically forms a complex with amino acids 1-87 of PTHLP which does not form a complex with amino acids 1-34 of PTHLP, and which forms a complex with the epitope to which any of the monoclonal antibodies produced by the hybridomas 212-10.7, (ATCC Accession No. HB9930), 199-999 (ATCC Accession No. HB9929), 199-278 (ATCC Accession No. HB9931), is directed. This invention further provides methods of detecting PTHLP and of diagnosing and treating humoral hypercalcemia of malignancy.


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