The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 01, 1993
Filed:
Jan. 28, 1992
Wolf-Ulrich Nickel, Bad Soden am Taunus, DE;
Hansjorg Urbach, Kronberg/Taunus, DE;
Dieter Ruppert, Kronberg/Taunus, DE;
Bernward Scholkens, Kelkheim, DE;
Hoechst Aktiengesellschaft, Frankfurt am Main, DE;
Abstract
Dipeptide derivatives having an enzyme inhibitory action Compounds of the formula I ##STR1## in which R.sup.1 represents a (substituted) heterocyclyl-alkyl, -alkoxy, -cycloalkyl or -cycloalkoxy and the corresponding heterocyclylmercapto radicals, A and B independently of one another denote an amino acid, R.sup.2 is hydrogen, alkyl, cycloalkyl, cycloalkyl-alkyl, aryl or aryl-alkyl, R.sup.3 represents hydrogen, alkyl, aryl, aryl-alkyl or hydroxyl and R.sup.4 denotes a radical (CH.sub.2).sub.0-4 CHR.sup.5 -D where R.sup.5 =hydrogen, alkyl, alkoxy, alkylthio, alkylamino, hydroxyl, azido or halogen and D=(substituted) heterocyclyl, have enzyme-inhibiting properties. Processes for the preparation of compounds of the formula I and their use in the treatment of hypertension and viral diseases are described.