The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 01, 1993

Filed:

Feb. 12, 1990
Applicant:
Inventors:

Walter Muller, Neuwied, DE;

Heinrich Kindel, Rengsdorf, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F / ;
U.S. Cl.
CPC ...
424443 ; 424449 ; 424448 ;
Abstract

The present invention relates to a therapeutic system for the retarded and controlled transdermal and transmucous administration of active substances via an impermeable backing layer, an active substance containing reservoir, a substantially drug-free but drug-permeable layer, and a removable protective layer, whereby the drug-free layer is brought into contact with the active substance reservoir only immediately prior or after application and then lies between reservoir and application surface, whereby at least a portion of the active substance diffusing from the reservoir is converted in the retardation layer into a non-bioavailable form. In this connection, the conversion into the non-bioavailable form may be carried out either by immobilization of the active substance, by chemical reactions, or by physical interactions.


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