The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 1993
Filed:
Jan. 13, 1992
Applicant:
Inventors:
Michel Page, Charlesbourg, CA;
Denis Thibeault, Ste-Foy, CA;
Assignee:
Universite Laval, Quebec, CA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
5303919 ; 530327 ; 530345 ; 530394 ; 530395 ; 530405 ; 530406 ; 530409 ; 530410 ; 424 8591 ; 514-2 ; 514-8 ; 514 12 ; 514 21 ; 536-64 ; 435961 ;
Abstract
The present invention relates to antitumor compounds of the formula I: ##STR1## wherein M is selected from the group consisting of an hydrogen atom, a peptide residue, and a protein residue linked to the carbon atom via the amino residue of .epsilon.-lysine present therein which can be an antibody used to target the anti-tumor agent to the malignant cells, and R can be an antitumor agent such as daunorubicin, doxorubicin, or an epirublicin derivative.