The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 1993
Filed:
Sep. 04, 1991
Seiji Shibahara, Yokohama, JP;
Yoshiyuki Koyama, Yokohama, JP;
Shigeharu Inoue, Yokohama, JP;
Mitsugu Hachisu, Yokohama, JP;
Shinichi Kondo, Yokohama, JP;
Takaaki Aoyagi, Fujisawa, JP;
Tomio Takeuchi, Tokyo, JP;
Zaidan Hojin Biseibutsu Kagaku Kai, both of, JP;
Meiji Seika Kaisha Ltd., both of, JP;
Abstract
A novel actinonin derivative and a salt thereof are provided, which are useful as enzyme inhibitors and particularly have strong inhibitory activities against enkephalinase and angiotensin-converting enzymes. This actinonin derivative is represented by general formula (I): ##STR1## wherein R.sup.1 is sulfoxymethyl or carboxyl or a substituted carboxyl group selected from carboxamide, hydroxyaminocarbonyl and alkoxycarbonyl groups; and R.sup.2 is hydroxyl, alkoxy, hydroxyamino or sulfoxyamino group.