The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 1993

Filed:

Jan. 14, 1992
Applicant:
Inventors:

Peter Critchley, Bedford, GB;

Anthony V Rawlings, Raunds, Northants, GB;

Ian R Scott, Allendale, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424401 ; 424 59 ; 424 61 ; 424 69 ; 424 70 ; 424501 ; 514 24 ; 514 25 ; 514119 ;
Abstract

Novel pseudoceramides are compounds with a general structure (2): ##STR1## In this formula a is 0 or 1, b is 0 or 1 but if a is 0, b is also 0 and R has 1 to 8 carbon atoms. The substituents R and R.sup.1 are a range of substituted or unsubstituted aliphatic hydrocarbon substituents. R.sup.2 is hydrogen, a sugar residue, a sulphate residue or a phosphate residue. R.sup.3 is hydrogen or a fairly short chain hydrocarbon substituent which in turn may be substituted. All of the substituents R--R.sup.3 are more fully defined in claim 1. These novel compounds are effective to improve water barrier function of the stratum corneum. They may be incorporated into compositions for topical application to human skin, hair and nails. A synthetic route for obtaining the novel compounds is described.


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