The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 1993
Filed:
Sep. 16, 1991
Mark G Bock, Hatfield, PA (US);
Ben E Evans, Lansdale, PA (US);
Roger M Freidinger, Lansdale, PA (US);
Kevin Gilbert, Bechtelsville, PA (US);
Doug W Hobbs, Lansdale, PA (US);
James B Hoffman, King of Prussia, PA (US);
George F Lundell, Blue Bell, PA (US);
Douglas J Pettibone, Chalfont, PA (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
Compounds of the formula: ##STR1## where R.sup.1 is hydrogen or hydroxy and R.sup.2 is a substituted amino group, a substituted heterocyclic ring or a substituted alkyl. These compounds are oxytocin and vasopressin antagonists useful in the treatment of preterm labor, dysmenorrhea and for the stoppage of labor preparatory to cesarean delivery, timing of parturition, uterine hyperactivity, endometriosis, hypertension, congestive heart failure, hyponatremia and cognitive disorders. Also disclosed are pharmaceutical compositions containing these compounds, methods of their use and methods of their preparation.