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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5204097 B1

PDFFull Text
Date of Patent:
Apr. 20, 1993

Filed:

Jun. 09, 1989

Shiga toxin b chain polypeptides and vaccine thereto

Applicant:
Inventors:

Ruth Arnon, Rehovot, IL;

Ilana Harari, Kfar Aviv, IL;

Gerald T Keusch, Lexington, MA (US);

Arthur Donohue-Rolfe, Sudbury, MA (US);

Assignee:

Yeda Research and Development Company Limited, Rehovot, IL;

Attorney:

Browdy and Neimark

Primary Examiner:

Garnette Draper

Int. Cl.
CPC ...
A61K / ; C07K / ; C08H / ;
U.S. Cl.
CPC ...
424 92 ; 530323 ; 530326 ; 530327 ; 530328 ; 530345 ; 530402 ; 530403 ; 530404 ; 530405 ; 530825 ; 424 88 ; 527200 ; 527202 ; 514-2 ; 514 13 ; 514 14 ; 514 15 ;
Abstract

The invention relates to a number of synthetic polypeptides which correspond to a part of the sequences of the Shiga B peptide chain. More specifically, the invention relates to polypeptides corresponding to the residues 5 to 18, 7 to 26, 13 to 26, and 19 to 29 of said B chain. The invention further relates to the conjugates of each of these with a suitable carrier and to polymers of each or these obtained by polymerization with a suitable polymerization agent: these can be used as effective vaccines which afford protection against Shiga toxin. Anti-peptide anti-sera are effective in neutralizing to a large extent the biological activity of Shiga toxin.

Find Patent Forward Citations

Arnon, Ruth. (1993). Shiga toxin b chain polypeptides and vaccine thereto (U.S. Patent No. 5204097). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5204097

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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