The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 1993
Filed:
Jun. 13, 1991
Applicant:
Inventors:
John H Hutchinson, Montreal, CA;
Yves Girard, Bizard, CA;
Rejean Fortin, Montreal Nord, CA;
Dwight MacDonald, Ile Bizard, CA;
John Scheigetz, Dollard des Ormeaux, CA;
Daniel Delorme, St. Lazare, CA;
Michel Therien, Laval, CA;
Pierre Hamel, Vimont, CA;
Assignee:
Merck Frosst Canada, Inc., Kirkland, CA;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
5147275 ; 5142378 ; 514253 ; 514321 ; 514338 ; 514411 ; 514826 ; 514886 ; 544 60 ; 544111 ; 544372 ; 546189 ; 546194 ; 546198 ; 548431 ; 548436 ;
Abstract
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, psoriasis, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.