The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 1993
Filed:
Oct. 09, 1990
Applicant:
Inventors:
Umberto Valcavi, Milan, IT;
Vincenzo Monterosso, Nova Milanese, IT;
Roberto Caponi, Milan, IT;
Enrico Bosone, Milan, IT;
Wilfried Wachter, Bergisch Gladbach, DE;
Jozsef Szejtli, Budapest, HU;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C08B / ;
U.S. Cl.
CPC ...
514 58 ; 536103 ;
Abstract
The invention relates to inclusion complexes of Silybinin with a cyclodextrin selected from the group consisting of .alpha.-, .beta.- and .gamma.-cyclodextrin and a suitable derivative thereof and to the method for the preparation thereof. The inclusion complexes of Silybinin showed a highly improved bioavailability in comparison to Silybinin which makes them particularly interesting in the treatment of various hepatotoxic conditions.