The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 1993

Filed:

Jun. 09, 1989
Applicant:
Inventors:

Masuo Aizawa, Suginami-ku, Tokyo 167, JP;

Brenda D Manning, North Easton, MA (US);

Miki Hidaka, Los Angeles, CA (US);

Laura S Uretsky, Milford, MA (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
436518 ; 435817 ; 436537 ; 436538 ; 436544 ; 436806 ; 436817 ; 436818 ; 530363 ; 530807 ; 530812 ;
Abstract

A method is described for measuring the amount of analyte present in a sample containing the analyte using a homogeneous amperometric immunoassay. The analyte is covalently bonded to a suitable carrier molecule, which is also covalently bonded to an electroactive molecule. The electroactive molecule, such as ferrocene carboxylic acid, contains a redox center which is capable of transferring a charge to an electrode. A preferred carrier molecule is bovine serum albumin (BSA), while suitable analytes include digoxin, theophylline and HCG. The immunoassay is conveniently performed by applying a voltage to a set of electrodes.

Published as:
CA2017525A1; EP0402126A1; AU5608190A; JPH0325360A; US5198367A; AU641395B2; MX174477B; US5346832A; EP0402126B1; DE69026309D1; DE69026309T2; JP2550428B2;

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