The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 1993

Filed:

Jul. 13, 1990
Applicant:
Inventors:

Eric J Hansen, Plano, TX (US);

Robert S Munford, Dallas, TX (US);

Jussi Mertsola, Kaarina, FI;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-72 ; 435-791 ; 435-732 ; 435-735 ; 435810 ; 435879 ; 435-737 ; 435-792 ; 435-794 ; 435 23 ; 435 24 ; 436501 ; 436518 ; 436 71 ; 436815 ; 436821 ;
Abstract

The invention relates to a method of detecting gram-negative bacterial endotoxin using antibody capture combined with amoebocyte lysate chromogenic detection. The method is highly sensitive and rapid and may be used for detection of specific endotoxin. In a particular application, picogram levels of Haemophilus influenzae are detected in plasma taken from previously infected mammals.


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