The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 16, 1993
Filed:
Oct. 07, 1991
Applicant:
Inventors:
Gino M Salituro, Fanwood, NJ (US);
Francis Dumont, Rahway, NJ (US);
George M Garrity, Westfield, NJ (US);
Leeyuan Huang, Watchung, NJ (US);
E Tracy Jones, Edison, NJ (US);
Mary N Omstead, Westfield, NJ (US);
Isabel M Fernandez, Madrid, ES;
Teresa D Matas, Madrid, ES;
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ;
U.S. Cl.
CPC ...
435118 ; 4352535 ; 435886 ;
Abstract
Described is a new process for producing the macrolide immunosuppressant, FK-506 under fermentation conditions utilizing the microorganism, Streptomyces sp., (Merck Culture Collection No. MA 6858) ATCC No. 55098. The immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e.g. bone marrow and heart transplants.